

Some facts about Colchicine drug should be said:
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Usual Adult dosage for Gout - Prophylaxis - Oral: 0.5 to 0.6 mg orally once a day for 3 to 4 days a week (less than 1 attack/year). 0.5 to 0.6 mg orally once a day (greater than 1 attack/year). Severe cases may require 1 to 1.8 mg/day.
Colchicine (Colcrys) Hematologic side effects have included thrombocytopenia, pancytopenia, leukopenia, agranulocytosis, bone marrow failure, bone marrow depression, disseminated intravascular coagulation, and aplastic anemia in patients on long-term therapy and are most common in cases of overdose or intoxication. Heinz-body hemolytic anemia has been reported in 3 cases.
Dialysis. Gout Flares: The recommended dosage for patients undergoing dialysis should be reduced to a single dosage of 0.6 mg. For these patients, a treatment course should not be repeated more than once every 2 weeks.
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And here are several reviews about Colchicine medicine from some patients:
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Colchicine for Gout, Prophylaxis: This is a great drug for gout flareups. The problem is that the cost went from 5 cents per pill to $5.50 per pill
Colchicine for Gout, Acute: I get several gout attacks a year. Less side effects but also not as fast acting as Colchicine (Colcrys) was. Taking more Colcry over several days to obtain relief then when I was taking Colchicine (Colcrys).
Really helps knock down the acute attacks of gout. doctor says as soon as I start getting sick is time to stop taking it.
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Also if you're not tired of reading - here are a few in some way funny expressions about health and medications from various famous men and women:
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Michelle Obama: The truth is, in order to get things like universal health care and a revamped education system, then someone is going to have to give up a piece of their pie so that someone else can have more.
Hippocrates: If we could give every individual the right amount of nourishment and exercise, not too little and not too much, we would have found the safest way to health.
Quentin Crisp: Health consists of having the same diseases as one's neighbors.
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And here we have some more words about Colchicine (Colcrys) drug should be said:
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Renal dosage Adjustments. Gout Flares: Mild (CrCl 50 to 80 mL/min) to moderate (CrCl 30 to 50 mL/min) renal impairment: No dosage adjustment required, but patients should be monitored closely for adverse effects. Severe (CrCl less than 30 mL/min) renal impairment: No dose adjustment required, but a treatment course should not be repeated more than once every 2 weeks. For patients requiring repeated courses, consideration should be given to alternate therapy.
Colchicine Nervous system side effects have rarely included myopathy, seizures, mental status changes, and neuropathy in patients with impaired renal function, and are sometimes reversible with drug discontinuation. Neuromyopathy occurrence has been reported with or without elevated muscle enzymes.
Usual Adult dose for Acute Gout. Oral: Initial: Gout Flare: 1.2 mg orally at the first sign of the flare followed by 0.6 mg one hour later. Maximum: Gout Flare: 1.8 mg orally over a one hour period.
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And of course some more feedbacks about Colchicine (Colcrys) tabs from different people:
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I have taken Colchicine (Colcrys) off and on during flares, and it seems that it has helped , but it sure makes intestinal problems. I don't want to go out anywhere while taking this medication.
Been on it for almost 3 months now for reacurring pericarditis. It has helped lesson the pain when i have a flare up, so it does help. But had to get my dosage right first, had horrible side effects until i figured out my dose!
I have been suffering from gout for past 10 years. One instance the pain was so bad I had to call the on call physician. I was diagnosed with gout. I was prescribed Colchicine (Colcrys) for the pain. The pain stopped and the swelling decreased. I now take the medication daily and have no problems. I have no complains since I have been on this medication. I'll deal with the side effects of the medication than the severe pain from the gout which is unbearable.
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