

Several words about Colchicine drug in general:
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Dialysis. Familial Mediterranean Fever: The total recommended starting dose should be 0.3 mg/day. Dosing may be increased with close monitoring. Any increase in dose should be done with adequate monitoring of the patient for adverse effects.
Renal dosage Adjustments. Familial Mediterranean Fever: Mild (CrCl 50 to 80 mL/min) to moderate (CrCl 30 to 50 mL/min) renal impairment: No dose adjustment required, but patients should be monitored closely for adverse effects. dose reduction may be necessary. Severe (CrCl less than 30 mL/min) renal impairment: Dosage should be started at 0.3 mg/day; any increase in dosage should be done with adequate monitoring of the patient for adverse effects. In patients with renal impairment who are taking protease inhibitors for the treatment of HIV-1 infection, the FDA has recommended against the coadministration of Colchicine.
Call your healthcare professional at once if you have a serious side effect such as muscle pain or weakness, numbness or tingly feeling in your fingers or toes, severe vomiting or diarrhea, easy bruising or bleeding, feeling weak or tired, flu symptoms, blood in your urine, urinating less than usual or not at all, or a pale or gray appearance of your lips, tongue, or hands.
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And here are a few feedbacks about Colchicine (Colcrys) drug from some people:
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I have been suffering from gout for past 10 years. One instance the pain was so bad I had to call the on call physician. I was diagnosed with gout. I was prescribed Colchicine (Colcrys) for the pain. The pain stopped and the swelling decreased. I now take the medication daily and have no problems. I have no complains since I have been on this medication. I'll deal with the side effects of the medication than the severe pain from the gout which is unbearable.
I take a .6mg tab of Colchicine in the a.m. It has been very helpful in relieving what was my greatest challenge, searing pain in the ankles whenever weightbearing. Has given me a new lease on life. Sorry it took so long to find (9years) and 3 rheumatologists to find out about it.
Been on it for almost 3 months now for reacurring pericarditis. It has helped lesson the pain when i have a flare up, so it does help. But had to get my dosage right first, had horrible side effects until i figured out my dose!
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Also if you're not tired of reading - here are several informative expressions about health and medications from various well known persons:
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Terri Guillemets: My own prescription for health is less paperwork and more running barefoot through the grass.
Joan Collins: I think health is another exceedingly important thing.
Cher: Fitness - If it came in a bottle, everybody would have a great body.
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And here we have some more words about Colchicine (Colcrys) tabs in general:
Before moving on to finding Canadian Pharmacy in North Carolina for Colchicine consider the following info:
Liver dosage Adjustments. Familial Mediterranean Fever: Mild to moderate hepatic impairment: No dosage adjustment required, but patients should be monitored closely for adverse effects. dose reduction may be necessary. Severe hepatic impairment: dose reduction should be considered. In patients with hepatic impairment who are taking protease inhibitors for the treatment of HIV-1 infection, the FDA has recommended against the coadministration of Colchicine (Colcrys).
Colchicine Gastrointestinal side effects have included diarrhea, nausea, vomiting, and abdominal pain in nearly 80% of treated patients, and can be indicative of acute Colchicine toxicity. Anorexia, electrolyte disturbance, pancreatitis, and paralytic ileus may also occur, and steatorrhea and enzyme inhibition have been reported in patients on long-term Colchicine (Colcrys) prophylaxis.
The current FDA-approved dosage for gout flare is substantially lower than what has been historically used clinically. doses higher than 1.8 mg over a 1 hour period for gout flare are not proven more effective and are not recommended.
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And of course a few more experiences about Colchicine drug from some men and women:
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I do feel this works pretty steady for me.. Not really any stomach issues, just the occassional need to use the toilet often... so I time it and usually stay home when taking this. Im sure to drink lots of water.
Really helps knock down the acute attacks of gout. doctor says as soon as I start getting sick is time to stop taking it.
Colchicine for Gout, Acute: I am subject to relatively frequent gout flare up, every 2-3 months or so. At the first symptoms I take one 0.5 mg of Colchicine every three hours and most of the time after 2-3 pills the pain is gone. I also take 1-2 pills of imodium to avoid the diarrhea.It works fine for me
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